PUBLICATIONS

  • "The Functional Mammalian CRES (Cystatin-Related Epididymal Spermatogenic) Amyloid is Antiparallel β-Sheet Rich and Forms a Metastable Oligomer During Assembly." Do HQ, Hewetson A, Myers C, Khan NH, Hastert MC, M Harsini F, Latham MP, Wylie BJ, Sutton RB, Cornwall GA (2019) Sci Rep. DOI: 10.1038/s41598-019-45545-w

  • "A DNA aptamer reveals an allosteric site for inhibition in metallo-β-lactamases." Khan NH, Bui AA, Xiao Y, Sutton RB, Shaw RW, Wylie BJ, Latham MP (2019) PLoS One. DOI: 10.1371/journal.pone.0214440.

  • "Increasing the buffering capacity of minimal media leads to higher protein yield." Azatian SB, Kaur N, Latham MP (2019) J Biomol NMR. DOI: 10.1007/s10858-018-00222-4

  • "Methyl-based NMR spectroscopy methods for uncovering structural dynamics in large proteins and protein complexes." Boswell Z and Latham MP (2018) Biochemistry. DOI:10.1021/acs.biochem.8b00953

  • "The structural basis of CstF-77 modulation of cleavage and polyadenylation through stimulation of CstF-64 activity." Grozdanov PN, Masoumzadeh E, Latham MP, MacDonald CC (2018) Nucleic Acids Res. 46(22):12022-12039. doi: 10.1093/nar/gky862

  • "A dynamic allosteric pathway underlies Rad50 ABC ATPase function in DNA repair." Boswell ZK, Rahman S, Canny MD, Latham MP (2018) Sci Rep. Jan 26;8(1):1639.

  • "Inhibition of 53BP1 favors homology-dependent DNA repair and increases CRISPR-Cas9 genome-editing efficiency." Canny MD, Moatti N, Wan LCK, Fradet-Turcotte A, Krasner D, Mateos-Gomez PA, Zimmermann M, Orthwein A, Juang YC, Zhang W, Noordermeer SM, Seclen E, Wilson MD, Vorobyov A, Munro M, Ernst A, Ng TF, Cho T, Cannon PM, Sidhu SS, Sicheri F, Durocher D. (2018) Nat Biotechnol. 2018 Jan;36(1):95-102.

  • "A similar in vitro and in cell lysate folding intermediate for the FF domain." Latham MP, Kay LE (2014) J Mol Biol. 426(19):3214-20.

  • "Viscosity-dependent kinetics of protein conformational exchange: microviscosity effects and the need for a small viscogen." Sekhar A, Latham MP, Vallurupalli P, Kay LE (2014) J Phys Chem B. 118(17):4546-51.

  • "Nucleosome Acidic Patch Promotes RNF168- and RING1B/BMI1-Dependent H2AX and H2A Ubiquitination and DNA Damage Signaling." Leung JW, Agarwal P, Canny MD, Gong F, Robison AD, Finkelstein IJ, Durocher D, Miller KM. (2014) PLOS Genetics, 10(3).

  • "Understanding the mechanism of proteasome 20S core particle gating." Latham MP, Sekhar A, Kay LE (2014) Proc Natl Acad Sci USA. 111(15): 5532-7.

  • "Phosphorylation releases constraints to domain motion in ERK2." Xiao Y, Lee T, Latham MP, Warner LR, Tanimoto A, Pardi A, Ahn NG (2014) Proc Natl Acad Sci USA. 111(7): 256-11.

  • "53BP1 is a reader of the DNA damage-induced H2A Lys15 ubiquitin mark." Fradet-Turcotte A, Canny MD, Escribano-Díaz C, Orthwein A, Leung CC, Huang H, Landry MC, Kitevski-LeBlanc J, Noordermeer SM, Sicheri F, Durocher D. (2013) Nature, 499:50-4.

 

  • "Probing non-specific interactions of Ca²⁺ -calmodulin in E. coli lysate." Latham MP, Kay LE (2013) J Biomol NMR. 55(3): 239-47.

  • "Is buffer a good proxy for a crowded cell-like environment? A comparative NMR study of calmodulin side-chain dynamics in buffer and E. coli lysate." Latham MP, Kay LE (2012) PLoS One. 7(10): e48226.

  • "NMR chemical exchange as a probe for ligand-binding kinetics in a theophylline-binding RNA aptamer." Latham MP, Zimmermann GR, Pardi A (2009) J Am Chem Soc. 131(14): 5052-3.

  • "Comparison of alignment tensors generated for native tRNAval using magnetic fields and liquid crystalline media." Latham MP, Hanson P, Brown DJ, Pardi A (2008) J Biomol NMR. 40(2): 83-94.

 

  • "NMR methods for studying the structure and dynamics of RNA." Latham MP, Brown DJ, McCallum SA, Pardi A (2005) Chembiochem. 6(9): 1492-505.

Texas Tech University

Department of Chemistry and Biochemistry

Lubbock, Texas